Imaging Mass Microscope
The iMScope QT system is an atmospheric pressure MALDI-MS imaging system equipped with an optical microscope. You can easily attach and detach the LCMS Q-TOF, switching between mass spectrometry imaging and LC/MS analysis. The versatility of the system enables you to perform a broad range of applications.
With the iMScope QT system, you can also capture high-resolution images for efficient data analysis – with pixels that are five microns in size. These fine details enable you to accurately assess your sample.
| Laser Repetition Frequency | Max. 20 kHz |
|---|---|
| Laser Diameter | Min. ≤ 5 µm, Max. ≥ 100 µm |
| Imaging Acquisition Maximum Speed | ≥ 50 pixel/sec* |
| Microscope Magnification | Three levels (×5, ×10, ×40) |
* When a single m/z image of m/z 400 is captured with laser fired for 2 msec at 5 μm pitch, and 10000 pixels in the High-speed mode and no data matrix generated
The iMScope QT system contains an optical microscope that enables you to easily take microscope images to identify morphology to guide MALDI-MSI analysis.
IMAGEREVEAL allows for easy analysis between microscope and MSI images.
The 20kHz laser in the iMScope QT, in combination with the LCMS-9030/9050, enables rapid data collection while maintaining high sensitivity. The use of atmospheric pressure MALDI prevents matrix sublimation to facilitate complete sample analysis without loosing data quality.
Shimadzu offers a complete imaging solution from matrix application to data analysis. The iMLayer and iMLayer Aero offer two approaches for automated matrix application. The iMLayer provides a solution for matrix sublimation, with integrated technology to monitor matrix layer thickness for reproducible results and high spatial resolution imaging. The iMLayer Aero allows for both sample derivatization and matrix application through automated spraying. The combination of the iMLayer and iMLayer Aero through a two-step matrix application gives both high spatial resolution and high sensitivity for imaging analysis. IMAGEREVEAL is a powerful solution for data analysis offering a vendor neutral and easy to use software. Multiple analysis modes offer a complete analysis solution to simplify data analysis.
The Role of Automated Sample Preparation in Mass Spectrometry With Dr. Pierre Chaurand
The Technology Networks team attended ASMS 2025 and caught up with Dr. Pierre Chaurand, Full Professor in the Department of Chemistry at the University of Montreal. In this conversation, Dr. Chaurand underscores the critical importance of minimizing variability in analytical workflows and highlights how automated sample preparation can significantly improve reproducibility and efficiency.
The Pros and Cons of Atmospheric Pressure Ionization With Dr. Pierre Chaurand
At ASMS 2025, the Technology Networks team caught up with Dr. Pierre Chaurand, Full Professor in the Department of Chemistry at the University of Montreal. He shared insights into the strengths and limitations of the atmospheric pressure ionization method and how it can help to advance his research.
Imaging Mass Spectrometry in Spatial Biology With Dr. Pierre Chaurand
The Technology Networks team attended ASMS 2025 and spoke with Dr. Pierre Chaurand, Full Professor in the Department of Chemistry at the University of Montreal. In this video, he discusses how imaging mass spectrometry can be used in tandem with other complementary methodologies to advance spatial biology research.
Mapping Biomolecules and the Importance of Sample Prep With Dr. Pierre Chaurand
At ASMS 2025, the Technology Networks team caught up with Dr. Pierre Chaurand, Full Professor in the Department of Chemistry at the University of Montreal. In this video, Dr. Chaurand discusses the application of imaging mass spectrometry to study the molecular composition of tissue sections. He also highlights the importance of sample preparation and shares his primary techniques.
Mass Spectrometry Imaging: Paving the Way for the Next Generation
Inheriting the concept of a mass spectrometer equipped with an optical microscope from the iMScope series, the iMScope QT is also Shimadzu's flagship model for MS imaging with a Q-TOF MS.
High-End Imaging with an Unequaled Combination of Speed, Sensitivity, and Resolution
With unparalleled speed, sensitivity, and spatial resolution, the iMScope QT provides fast acquisition of high-mass, high-resolution images at the optical and molecular level and the ability to simultaneously visualize and analyze samples. Integration with the Q-TOF LCMS-9030 enables obtaining distribution information and quantitative data for comprehensive analysis.
Accelerate Throughput and Discovery for Your Mass Spec Imaging Projects with the iMScope QT
This video shows how the iMScope QT imaging mass microscope, by combining optical microscopy and mass spectrometry in a single unit, can accelerate your imaging research.
In addition to traditional mass spectrometry imaging experiments such as biomarker tracking, pharmacokinetics, and ADME studies, the versatility of the iMScope QT opens its usefulness up to other industries, including chemical products, food engineering, forensic sciences and more.
ASMS 2023 Hospitality Suite Tour
Watch this video for an overview of Shimadzu’s key mass spectrometry instruments, platforms, and software on display at the ASMS conference in Houston.
US HUPO One World (Human Proteome Organization) Conference
February 22-25
Philadelphia Lowes Hotel
Philadelphia, PA
Shimadzu Introduces iMScope™ QT Imaging Mass Microscope for High-Level Mass Spectrometry Imaging Analysis
Shimadzu Scientific Instruments introduces the iMScope QT imaging mass microscope designed for use with Shimadzu’s Q-TOF LCMS-9030mass spectrometer for fast acquisition of high-mass, high-resolution images at the optical and molecular level. When paired with the Q-TOF LCMS-9030, the iMScope QT provides a complete, high-end analytical solution combining precise tools and data processing that is unrivalled in the marketplace.
3 Good health and well-being
Powered by Bioz
